Cortagen (20 mg Vial) Dosage Protocol

Quickstart Highlights

Cortagen dosage protocols are designed around this synthetic tetrapeptide (Ala-Glu-Asp-Pro) that belongs to the Khavinson bioregulator class, studied for its neuroprotective and neuroregenerative properties^[1]^[2]. Research indicates Cortagen may support peripheral nerve regeneration, enhance cognitive function, reduce oxidative stress in neural tissues, and promote cellular repair mechanisms without significant adverse effects at therapeutic doses^[3]^[4]. This educational protocol presents a once-daily subcutaneous approach using a practical dilution for clear insulin-syringe measurements.

Reconstitute: Add 3.0 mL bacteriostatic water → 6.67 mg/mL (6670 mcg/mL) concentration.

Typical daily range: 1000–2000 mcg once daily (morning administration preferred).

Easy measuring: At 6.67 mg/mL, 1 unit = 0.01 mL ≈ 66.7 mcg on a U-100 insulin syringe.

Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); avoid freeze–thaw cycles.

Dosing & Reconstitution Guide

Educational guide for reconstitution and daily dosing

Standard Approach (3 mL = 6.67 mg/mL)

Week	Daily Dose (mcg)	Units (per injection) (mL)
Weeks 1–2	1000 mcg	15 units (0.15 mL)
Weeks 3–4	2000 mcg	30 units (0.30 mL)

Frequency: Inject once daily subcutaneously, preferably in the morning^[5]. This schedule uses the largest practical dilution (3.0 mL) to keep per-injection units ≥15 for accurate measurement. For doses under ~10 units (<700 mcg), consider using 50-unit or 30-unit insulin syringes for improved readability.

Reconstitution Steps

Draw 3.0 mL bacteriostatic water with a sterile syringe.

Inject slowly down the vial wall; avoid foaming.

Gently swirl/roll until dissolved (do not shake).

Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.

Important: This guide is for educational purposes only and is not medical advice. For research use only. Not for human consumption.

Supplies Needed

Plan based on a 4-week daily protocol with gradual titration (1000–2000 mcg/day).

Peptide Vials (Cortagen, 20 mg each):

4 weeks ≈ 3 vials (at average 1500 mcg/day = 42 mg total)
8 weeks ≈ 5 vials

Insulin Syringes (U-100):

Per week: 7 syringes (1/day)
4 weeks: 28 syringes
8 weeks: 56 syringes

Bacteriostatic Water (10 mL bottles): Use 3.0 mL per vial for reconstitution.

4 weeks (3 vials): 9 mL → 1 × 10 mL bottle
8 weeks (5 vials): 15 mL → 2 × 10 mL bottles

Alcohol Swabs: One for the vial stopper + one for the injection site each day.

Per week: 14 swabs (2/day)
4 weeks: 56 swabs → recommend 1 × 100-count box
8 weeks: 112 swabs → recommend 2 × 100-count boxes

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Protocol Overview

Concise summary of the once-daily regimen.

Goal: Support neural regeneration, cognitive function, and cellular repair mechanisms over time^[1]^[3].

Schedule: Daily subcutaneous injections for 4 weeks (extend to 8 weeks if desired).

Dose Range: 1000–2000 mcg daily with optional gradual titration.

Reconstitution: 3.0 mL per 20 mg vial (6.67 mg/mL) for accurate unit measurements.

Storage: Lyophilized frozen; reconstituted refrigerated; avoid repeated freeze–thaw.

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